Studies show oral glutathione has only 20% bioavailability
Bounous G, Batist G, Gold P
Die Einnahme kann aufgrund des natrlicherweise leicht schwefligen Geruchs von Glutathion angenehm gestaltet werden, indem das Produkt zum Beispiel mit Apfelsaft gemischt wird, der den Eigengeruch effektiv abmildert
Figures 2, 4) availability is maintained by de novo synthesis from precursor amino acids, (glutamate, cysteine, and glycine), reduction of GSSG by glutathione reductase (GR), and uptake from exogenous GSH sources across plasma membranes (Figure 4) ( via specific plasma membrane transporters ( FIGURE 3 FIGURE 4 Glutathione cellular distribution Glutathione is found in almost all cellular compartments, including the nucleus (Figures 2, 4)
Rubenstein & Merzenich, 2003) involving either or both upregulated glutamatergic excitatory and down-regulated GABAergic inhibitory systems(Sohal & Rubenstein, 2019)